Varicella Zoster Virus (VZV) IgG ELISA kit is an enzyme immunassay for the in-vitro diagnostic qualitative and quantitative determination of IgG antibodies against Varicella zoster virus (VZV) in human serum and plasma. Varicella Zoster Virus (VZV) IgG ELISA kit is a solid phase enzyme-linked immunosorbent assay (ELISA) based on the sandwich principle. The wells of this Varicella Zoster Virus (VZV) IgG ELISA kit are coated with antigen. Specific antibodies of the sample binding to the antigen coated wells are detected by a secondary enzyme conjugated antibody (E-Ab) specific for human IgG. After the substrate reaction the intensity of the color developed is proportional to the amount of IgG-specific antibodies detected. Results of samples can be determined directly using the standard curve.

The Varicella Zoster Virus (VZV) IgG ELISA kit is shipped at ambient temperature and should be stored at 2-8°C. Keep away from heat or direct sunlight. The storage and stability of specimen and prepared reagents is stated in the protocol insert. The microtiter strips of this Varicella Zoster Virus (VZV) IgG ELISA kit are stable up to the expiry date of the kit in the broken, but tightly closed bag when stored at 2–8°C.

Varicella is an acute viral disease caused by the Varicella zoster virus (VZV) that belongs to the herpes virus family. The well-known disease begins with fever and malaise and a maculopapular rash that changes within hours to vesicles. Lesions pustulate, crust and heal slowly over a 3 week period. The disease is rarely fatal, however, the most common cause of death in adults is the primary viral pneumonia, and in children, secondary bacterial infections or central nervous system involvement. Children with acute leukemia or immunocompromised persons are at higher risk of a general dissemination of the disease with fatal outcome. Newborns that are infected after 5 to 10 days, and the ones born from mothers that were infected 5 days before or two days after birth, can develop severe generalised varicella with a mortality rate of 30%. Infection at the beginning of pregnancy rarely gives congenital malformations. Reactivation of VZV is usually manifested as zoster. Zoster normally begins with unilateral sharp and well localised pain. In this case the titer of the IgG antibodies is increased, whereas the titer of IgM antibodies is raised only in some few cases.