Source: E.Coli   Catalog No.: CYT-473   Introduction:

Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. This antibody reacts with the precursor and mature form of TGFBeta2 and to a lesser extent TGFBeta3, but does not cross react with TGFBeta1.

Description :

The TGF-β 1 is purified by standard chromatographic techniques and shows a 51 kDa band on SDS-PAGE (including tag).

Synonyms:

Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB.

Physical Appearance:

Sterile Filtered clear solution.

Formulation:

The protein solution (0.1mg/ml) contains 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.

Stability:

Recombinant TGF-b1 although stable at 4 °C for 1 week, should be stored desiccated below -18 °C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Purity:

Greater than 80.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Amino acid sequence:

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn.

Usage:

Product is furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.