Source: E.Coli   Catalog No.: CYT-495   Introduction:

TNF-β is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumor cells and a variety of other target cells as well as being a mediator of inflammation and immune function.

Description :

Tumor Necrosis Factor -β His Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 171 amino acids fragment (35-205) and having a molecular mass of 18.6 kDa with an amino-terminal hexahistidine tag.  The TNF-β His is purified by standard chromatographic techniques.

Synonyms:

Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA, LT, TNFB, TNFSF1.

Physical Appearance:

Sterile Filtered clear solution.

Formulation:

TNF-β is is supplied in 1x PBS and 50% glycerol.

Stability:

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze-thaw cycles.

Purity:

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Usage:

Product is furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.