Source: E.Coli   Catalog No.: CYT-314   Introduction:

CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.

Synonyms:

gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.

Description :

CD-4 Human Recombinant encoding amino acids 411-459.

Physical Appearance:

Sterile filtered liquid.

Formulation:

CD-4 Human Recombinant protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.

Stability:

Store vial at -20 °C to -80 °C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.

Application And Suggested Dilutions:

• ELISA • Inhibition Assays • Western Blotting

Characterization:

On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48kDa.

Usage:

Product is furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.