Source: E.Coli   Catalog No.: CYT-316   Introduction:

CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.

Synonyms:

gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.

Description :

CD-4 Human Recombinant His Tag protein encoding amino acids 203-317.

Physical Appearance:

Sterile lyophilized powder.

Formulation:

Each mg contains 1X PBS, 0.1% SDS and 1 mM DTT.

Stability:

Store vial at -20  °C to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.

Application And Suggested Dilutions:

• Protein Assay • Antibody Production • Western Blotting

Usage:

Product is furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.