Source: E.Coli   Catalog No.: CYT-449   Introduction:

IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-A, IFN-B, and IFN-G stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines.

Description:

Interferon Regulatory Factor-1 Human Recombinant produced in E.Coli is a single, non-glycosylated, His Tag, polypeptide chain containing 144 amino acids (1-144) and having a molecular mass of 15 kDa. The IRF-1 is purified by proprietary chromatographic techniques.

Synonyms:

IRF-1, IRF1, MAR.

Physical Appearance:

Sterile Filtered colorless solution.

Formulation:

1 mg/ml in 20mM Tris pH-8 and 10% glycerol.

Stability:

Liquid Interferon although stable at 10 °C for 1 week, should be stored below -18 °C.  For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).  Please avoid freeze-thaw cycles.

Purity:

Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Usage:

Product is furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.