APO D Human, GST
Synonyms:
Apolipoprotein D, Apo-D, ApoD.
Catalogue Number:
CYT-652
Description:
APO-D Human (APO D Human, GST) Recombinant full length protein expressed in E.coli, shows a 48 kDa band on SDS-PAGE. The APO-D is purified by proprietary chromatographic techniques.
Introduction:
Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid.
Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for transport to the blood or could transport a ligand from the circulation to specific cells within a tissue.
Source:
Escherichia Coli.
Physical Appearance:
APO D Human, GST is a sterile Filtered clear solution.
Formulation:
APO-D (APO D Human, GST) protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Applications for APO D Human, GST:
• ELISA
• Inhibition Assays
• Western Blotting.
Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
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