|
Name |
Expression |
M. W. |
Functions |
Family |
|
CD101 |
Granulocytes, macrophages |
140 |
Unknown |
|
|
CD102 |
Resting lymphocytes, monocytes, strongest on vascular endothelial cells
|
55-65 |
binds CD11a/CD18 (LFA-1) but not CD11b/CD18 (Mac-1) |
IgSF |
|
CD103 |
Intraepithelial lymphocytes, 2-6% of peripheral blood lymphocytes
|
150,25 |
aE integrin |
|
|
CD104 |
Epithelia, Schwann cells, some tumour cells |
220 |
b4 integrin |
|
|
CD105 |
Endothelial cells, bone marrow cell subset, in vitro activated
macrophages |
95, homo- dimer |
unknown, possibly ligand for an integrin |
|
|
CD106 |
Endothelial cells |
100,110 |
Adhesion molecule, ligand for VLA-4 |
IgSF |
|
CD107a |
Activated platelets |
110 |
Unknown, is lysosomal membrane protein translocated to the cell surface
after activation |
|
|
CD107b |
activated platelets |
120 |
Unknown, is lysosomal membrane protein translocated to the cell surface
after activation |
|
|
CDw108 |
Activated T cells in spleen, some stromal cells |
80 |
Unknown |
|
|
CD109 |
Activated T cells, platelets, endothelial cells |
170/50 |
Unknown |
|
|
CD114 |
G-CSF receptor |
|
|
|
|
CD115 |
monocytes, macrophages |
150 |
Macrophage Colony Stimulating Factor (M-CSF) receptor |
IgSF |
|
CD116 |
monocytes, neutrophils,eosinophils, endothelium |
70-85 |
Granulocyte, Macrophage Colony Stimulating Factor (GM-CSF) receptor
a chain |
cytokine receptor superfamily |
|
CD117 |
hematopoietic progenitors |
145 |
Stem Cell Factor (SCF) receptor |
IgSF tyrosine kinase |
|
CD118 |
Broad cellular expression |
|
Interferon a, b receptor |
|
|
CD119 |
marophages, monocytes, B cells, endothelium |
90-100 |
Interferon g receptor |
|
|
CD120a |
hematopoietic and non-hematopoietic cells, highest on epithelial cells
|
50-60 |
TNF receptor, binds both TNFa and TNFb |
NFG receptor superfamily |
|
CD120b |
hematopoietic and non-hematopoietic cells, highest on myeloid cells
|
75-85 |
TNF receptor, binds both TNFa and TNFb |
NFG receptor superfamily |
|
CD121a |
thymocytes ,T cells |
80 |
type I interleukin 1 receptor, binds IL-1a and IL-1b |
IgSF |
|
CDw121b |
B cells, macrophages, monocytes |
60-70 |
type II interleukin 1 receptor, binds IL-1a and IL-1b |
IgSF |
|
CD122 |
Natural killer cells, resting T cell subpopulation, some B cell lines
|
75 |
IL-2 receptor b chain |
|
|
CDw123 |
Bone marrow stem cells, granulocytes, monocytes, megakaryocytes
|
70 |
IL-3 receptor a chain |
cytokine receptor superfamily fibronectin type III superfamily
|
|
CD124 |
Mature B and T cells, haematopoietic precursor cells |
130-150 |
IL-4 receptor |
cytokine receptor superfamily fibronectin type III superfamily
|
|
CDw125 |
Eosinophils, basophils |
55-60 |
IL-5 receptor |
cytokine receptor superfamily fibronectin type III superfamily
|
|
CD126 |
Activated B cells and plsama cells, weak on most leukocytes |
80 |
IL-6 receptor a subunit |
IgSF cytokine receptor superfamily fibronectin type III superfamily
|
|
CD127 |
Bone marrow lymphoid precursors, pro-B cells, mature T cells,monocytes
|
68-79, possibly forms homodimers |
IL-7 receptor |
fibronectin type III superfamily |
|
CDw128 |
Neutrophils, basophils, T cell subset |
58-67 |
IL-8 receptor |
rhodopsin superfamily |
|
CDw130 |
Activated B cells and plasma cells; weak on most leukocytes; endothelial
cels |
130 |
IL-6 receptor b subunit |
IgSF
cytokine receptor superfamily
fibronectin type III superfamily |
|
CDw131 |
monocytes, granulocytes,
eosinophils, B cells, |
95-120 |
B and T cell growth |
|
|
CD132 |
T and B cells, fibroblasts haematopoietic precursors |
64 |
B and T cell growth |
|
|
CD134 |
activated T cells |
48-50 |
adhesion activated T cells;ligand for gp34 |
|
|
CD135 |
CD34 cells, carcinoma cells |
130-150 |
receptor tyrosine kinase |
|
|
CDw136 |
|
180 |
receptor tyrosine kinase |
|
|
CDw137 |
T cells |
30 |
co-stimulatory T cell activation |
|
|
CD138 |
plasma cells; syndecan 1 |
|
ligand for collagen type 1 |
|
|
CD139 |
|
|
|
|
|
CD140a |
|
180 |
PDGFRa |
|
|
CD140b |
|
180 |
PDGFRb |
|
|
CD141 |
myeloid cells, endothelial cells, smooth muscle cells |
100 |
myeloid thrombin receptor; regulation of coagulation |
|
|
CD142 |
monocytes, endothelial cells |
45 |
receptor for clotting factor VII, inhibits clotting |
|
|
CD143 |
endothelial and epithelial cells |
170 |
peptidyl-peptidase, ACE |
|
|
CD144 |
endothelial cells |
135 |
adhesion molecule;role in cell-cell adhesion |
|
|
CDw145 |
endothelial cells |
|
|
|
|
CD146 |
endothelial cells, melanoma cells, follicular dendritic cell
|
113-118 |
homing of activated T cells |
|
|
CD147 |
endothelial cells, myeloid cells, lymphocytes |
|
|
|
|
CD148 |
|
|
|
|
|
CDw149 |
|
|
|
|
|
CDw150 |
T and B cells |
75-95 |
signalling molecule |
|
|
CD151 |
|
|
PETA-3 |
|
|
CD152 |
T cells |
44 |
neg. regul. for T cells co stimul;ligand CD80,86 |
|
|
CD153 |
T cells |
40 |
co-stimulatory for T cells; ligand for CD30 |
|
|
CD154 |
T cells |
32-39 |
co-stimulatory molecule; ligand for CD40 |
TNF |
|
CD155 |
|
|
Polio virus receptor (PVR) |
|
|
CD156 |
|
|
ADAM8 |
|
|
CD157 |
|
|
MO-5, BST-1 |
|
|
CD158a |
T cells |
58/50 |
inhibition of cytotox; class-I specific NK-receptor |
|
|
CD158b |
T cells |
58/50 |
inhibition of cytotox; class-I specific NK-receptor |
|
|
CD158c |
T cells |
55-58 |
activating molecule;member of Ig superfamily |
|
|
CD161 |
NK cells |
60 |
regulation of NK cell-mediated cytotoxicity |
|
|
CD162 |
monocytes, granulocytes, T cells, subset of B cells |
240 |
adhesion molecule;leucocyte rolling; ligand P-selectin |
|
|
CD163 |
|
|
GHI/61, M130 |
|
|
CD164 |
myeloid cells, T cells, epithelial cells, bone marrow stroma cells
|
80 |
adhesion molecule haem progenitor cells to stroma |
|
|
CD165 |
T cells, NK cells, platelets, thymocytes, thymic epithelium |
37 |
adhesion molecule thymocytes/thymic epithelium |
|
|
CD166 |
T cells, NK cells, platelets, thymocytes, activated B and T cells, eosinophils,
fibroblasts, endothelial cells, keratinocytes |
100 |
adhesion molecule; ligand for CD6 |
|
