Acrp30 Human, His (Adiponectin)
- Originate from the apM1 gene, this gene has been found to show high expression within adipose cells and tissues. The Acrp30, human protein is part of the soluble defense collagen family.
- When there is a large weight loss this leads to an elevation of the levels of adiponectin being circulating within the body. There is also evidence to suggest process is carried out through the brain. Adiponectin is found to be secreted within the bloodstream and it represents about 0.01% of plasma proteins that is present. In diabetic patients the levels are significantly less when compared to non-diabetic.
- APM-1 has been found to form homotrimers, which can be the building blocks for higher order complexes found circulating in serum.
- Relatively newly identified family member which is a polypeptide protein that is 244 a.a. in length.
Formulation: Lyophilized and sterile filtered from 0.5 mg/ml in 0.15M NaCl. and 0.02M Tris that is buffered to pH7.5.
Solubility: Lyophilized pellet should be dissolved fully in 0.5mg/ml of deionized water (stock solution)
Stability: Store lyophilized at -20°C for long term storage and 4°C for short term. Please avoid repeated freezing/thawing cycles.
Applications: Western blot analysis.
Purity: More than 95% as determined by SDS PAGE and HPLC.
Amino Acid Sequence:
MRGSHHHHHHGSGHDQETTT QGPGVLLPLP KGACTGWMAG IPGHPGHNGA PGRDGRDGTP GEKGEKGDPG LIGPKGDIGE TGVPGAEGPR GFPGIQGRKG EPGEGAYVYR SAFSVGLETY VTIPNMPIRF TKIFYNQQNH YDGSTGKFHC NIPGLYYFAY HITVYMKDVK VSLFKKDKAM LFTYDQYQEN NVDQASGSVL LHLEVGDQVW LQVYGEGERN GLYADNDNDS TFTGFLLYHD TN.
Synonyms: GBP-28, AdipoQ, ACDC Acrp30, APM-1, Adiponectin.
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