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Adiponectin (Acrp30) Mouse, Trimeric Maximize

Adiponectin (Acrp30) Mouse, Trimeric

Mouse Adiponectin (Acrp30), Trimeric (Cat. No.# CYT-247) consist of 39 cysteine that has been changed to Alanine. The adiponectin is also sourced from HEK293 cells.

More details

  • Source : HEK293.
  • Purity : Greater than 95%.

CYT-247

10ug

£ 160.00

Acrp30 Mouse, Trimeric (Adiponectin)

Synonyms:  GBP-28, AdipoQ, ACDC Acrp30, APM-1, Adiponectin

Background:

  • APM-1 has been found to form homotrimers, which can be the building blocks for higher order complexes found circulating in serum.
  • Relatively newly identified family member which is a polypeptide protein that is 244 a.a. in length. The Acrp30, human protein is part of the soluble defense collagen family.
  • When there is a large weight loss this leads to an elevation of the levels of adiponectin being circulating within the body. There is also evidence to suggest process is carried out through the brain.  
  • Found to be secreted within the bloodstream and it represents about 0.01% of plasma proteins that is present. In diabetic patients the levels are significantly less when compared to non-diabetic.
  • Has also been found to originate from the apM1 gene, this gene has been found to show high expression within adipose cells and tissues.
     

Source: HEK293. 

Formulation: Lyophilized and sterile filtered from 0.5 mg/ml in 0.05M NaCl. and 0.05 M phosphate buffer that is buffered to pH7.2.

Solubility: Lyophilized pellet should be fully dissolved in 0.5mg/ml of deionized water (stock solution)

Stability: Store lyophilized at -20°C for long term storage and 4°C for short term. Please avoid repeated freezing/thawing cycles.

Applications: Binding assay, Ex vivo, In vivo analysis and In vitro analysis

Purity:  More than 95% as determined by SDS PAGE and HPLC.

Activity: ED50= 3-8.5 μg/ml determined by its ability to inhibit proliferation of HASMCs that have been induced by HB EGF.

Please contact us if you require any further information

  • Source : HEK293.
  • Purity : Greater than 95%.
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