ANGPT4 Human (Angiopoietin like 4)
Synonyms: ARP4, ANGPTL4, FIAF, PGAR, NL2, HFARP, ANGPTL2, Fasting- Induced Adipose Factor, PPARG Angiopoietin-Related Protein, pp1158, Angiopoietin-LIKE-4.
- Gene is known to code for the Angiopoietin like 4 protein in humans. This gene has also be called a number of other names in the past which include; HFARP, FIAF, PGAR and ANGPTL2.
- Also referred to as an adipo-cytokine because its levels are controlled by a state of fasting using either hypoxia or receptor agonists of peroxisome proliferators.
- Both the truncated and the native form of ANGPTL4 are present in the blood plasma of mouse and humans.
- The native form in humans is only detected in both the SGBS adipocytes and white adipose tissue, in contrast only the truncated ANGPTL4 is produced in mouse 3T3-L1 adipocytes.
Specificity: Homologous (100%) to a.a. sequence 26-229 of the Human ANGPTL4 precursor minus the signal sequence.
Purification Method: One-step using Ni-NTA chromatography.
Formulation: Lyophilized and sterile filtered from 0.5 mg/ml in 0.05M Acetate buffer pH-4.
Solubility: Dissolve lyophilized pellet fully in 0.2 ml of 0.1M Acetate buffer pH-4.
Stability: Store lyophilized at -20°C for long term storage and 4°C for short term. Please avoid repeated freezing/thawing cycles.
Purity: Above 95% as determined by SDS-PAGE.
Application: ELISA and Western blot analysis.
Amino Acid Sequence:
MRGSHHHHHH GMASHMGPVQ SKSPRFASWD EMNVLAHGLL QLGQGLREHA ERTRSQLSAL ERRLSACGSA CQGTEGSTDL PLAPESRVDP EVLHSLQTQL KAQNSRIQQL FHKVAQQQRH LEKQHLRIQH LQSQFGLLDH KHLDHEVAKP ARRKRLPEMA QPVDPAHNVS RLHRLPRDCQ ELFQVGERQS GLFEIQPQGS PPFLVNCKMT SDGGWTVIQR.
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